Antiplatelet and Anticoagulant Effects of Diterpenes Isolated from the Marine Alga, Dictyota menstrualis
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Antiplatelet and Anticoagulant Effects of Diterpenes Isolated from the Marine Alga, Dictyota menstrualis
Cardiovascular diseases represent a major cause of disability and death worldwide. Therapeutics are available, but they often have unsatisfactory results and may produce side effects. Alternative treatments based on the use of natural products have been extensively investigated, because of their low toxicity and side effects. Marine organisms are prime candidates for such products, as they are ...
متن کاملHeterofucans from Dictyota menstrualis have anticoagulant activity.
Fucan is a term used to denote a family of sulfated L-fucose-rich polysaccharides which are present in the extracellular matrix of brown seaweed and in the egg jelly coat of sea urchins. Plant fucans have several biological activities, including anticoagulant and antithrombotic, related to the structural and chemical composition of polysaccharides. We have extracted sulfated polysaccharides fro...
متن کاملChemotaxonomic study of the diterpenes from the brown alga Dictyota menstrualis.
Chemotaxonomic study of the diterpenes from the brown alga Dictyota menstrualis Valéria Laneuville Teixeira*, Diana Negrão Cavalcanti, Renato Crespo Pereira Departamento de Biologia Marinha, Universidade Federal Fluminense, C.P. 100.644, 24001-970, Niterói, RJ, Brazil b Programa de Pós-Graduação em Quı́mica Orgânica, Instituto de Quı́mica, Universidade Federal Fluminense, 24020-150, Niterói, RJ, ...
متن کاملDiterpenes from the Brown Alga Dictyota crenulata.
The crude extract of the Brazilian brown alga Dictyota crenulata was analyzed by NMR spectroscopy and HRGC-MS techniques. Seven diterpenes were identified: pachydictyol A, dictyodial, 4beta-hydroxydictyodial A, 4beta-acetoxydictyodial A, isopachydictyol A, dictyol C and dictyotadiol. Xeniane diterpenes have previously been found in D. crenulata from the Pacific Ocean. The results characterize D...
متن کاملCytotoxic hydroazulene diterpenes from the brown alga Dictyota dichotoma.
Two new hydroazulenoid (prenyl guaiane) diterpenes, dictyone acetate (2) and 3,4-epoxy 13-hydroxy pachydictyol A (4) were isolated from the petroleum ether fraction of the alcoholic extract of the brown alga, Dictyota dichotoma (Hudson) Lamouroux, which was collected from the Red Sea coasts at Hurgada, Egypt, together with three known ones, pachydictyol A (1), dictyone (3) and 11-hydroxypachydi...
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ژورنال
عنوان ژورنال: Marine Drugs
سال: 2014
ISSN: 1660-3397
DOI: 10.3390/md12052471